Skin disease
General Features
Although most skin diseases occur in the skin system, these abnormalities are also important in the diagnosis of many other skin diseases. There’s some truth within the conviction that skin reflects a person’s physical wellbeing. In common, the perceivability and accessibility of the skin makes it the primary zone of the body to appear indications of the basic malady.
Skin abnormalities often indicate metabolic, malignant, and glandular disorders.
The skin, like other tissues, is affected by many pathological changes, including genetic, inflammatory, benign and malignant (tumors), endocrine, hormonal, traumatic and degenerative processes.
Emotions can also affect the health of your skin. The skin’s response to these diseases and conditions differs from other tissues in several ways. For example, inflammation of the skin can affect the metabolism of other organs and systems in the body, causing blood deficiency, blood vessels, heat, and disruption of the water and electrolyte balance in the blood. However, the skin has such healing properties that serious injuries, such as a burn, can cause serious damage to the injury site or infection with insufficiently small scars.
Diagnosis
There are differences in certain anatomical areas of the skin that can alter the appearance of the rash.
This is what happens when the skin changes from one area of the body to another (except for different areas) retaining the characteristics of the donor area. Therefore, the morphology of palmar and plantar eczema or lichen planus may bear little or no resemblance to the confusion on the face or scalp of humans. In this case, a biopsy shows abnormalities in the skin cells and the structure and distribution of an invading cell.
The ability to detect antibodies (immunoglobulins or antibodies that cause specific antibodies or antigens) in skin biopsies improves the accuracy of inflammatory diseases and elucidates their central immunity, especially in vesicular diseases.
Classification of skin lesions is generally based on gross morphology, histology, and electron microscopic findings; however, some specific diagnoses are sometimes doubtful because dermatoses do not necessarily have characteristic presentations.
A better understanding of the biochemical disorders in genetic diseases of the skin now provides a more accurate diagnosis of these diseases. A group of ichthyosis is sometimes a dysfunctional group of skin disorders and can therefore be distinguished from other members of this group by biochemical testing for an enzyme deficiency (low steroid sulfatase).
Distribution
The distribution of the rash depends on the internal and external components of the body. Mechanical factors such as injury, environmental factors, fungus or disease, and drugs are the most exogenous determinants of distribution. Environmental influences, such as sunburn and photosensitivity, may also play an important role in drug-related reactions.
Rare diseases in the collective disease called psoriasis and epidermolysis bullosa, the distribution of which is due to local trauma; Symptoms found in epidermolysis bullosa Symptoms of epidermolysis bullosa. The rash after the site of mechanical or other physical injury is called isomorphic reactions. Symptoms of isomorphic disease include lupus erythematosus (sunburn), psoriasis, lichen planus, and flu (damage).
- Internal rather than external factors explain the characteristics of many rashes. Some red bumps with a parallel and segmental distribution can be attributed to the segmental arrangement of the embryo.
- It is the distribution of blood vessels in other rashes; for example, in herpes zoster (herpes zoster), the rash is determined by the distribution of the disease in the dorsal root ganglia. The blood supply to the skin has anatomical distribution characteristics that affect the pattern of some red bumps that constrict blood vessels or cause blood stasis.
Appearance
Skin diseases in which the epidermis is hypercellular or usually undifferentiated by scaling. Simple benign epidermal hyperplasia (overgrowth) often presents as lichenification, as in infantile eczema; this term is a term used to describe epidermal thickening in which the normal superficial markings of the skin are greatly exaggerated.
Some skin conditions are not associated with the disease, such as physical injury (such as heatstroke), allergies, and infections (such as fever and flu). Even skin cancer usually presents with some pain. Inflammation is usually caused by the release of chemicals in the skin.In some dermatoses, pain is the main symptom of the rash (for example, allergic dermatitis).
Inherited Skin Disorders
The development of almost all skin components (for example, hair texture and color and skin pigmentation and thickness) is genetically controlled. Many skin diseases are directly or indirectly determined by a person’s genotype (genetic predisposition), but their occurrence may require external influences or environmental hormonal changes..
Although genetics has a direct role in determining it, other factors can influence the disease. For example, lesions of skin nerves, which are usually directly controlled by genes, sometimes do not appear until hormonal changes during puberty create the right conditions for the expression of lines.
Read Also: Allergy symptoms, Types Best Guide in 2023
